PUBLICATIONS

Griffith EC, Zhao Y, Singh AP, Conlon BP, Tangallapally R, Shadrick WR, Liu J, Wallace MJ, Yang L, Elmore JM, Li Y, Zheng Z, Miller DJ, Cheramie MN, Lee RB, LaFleur MD, Lewis K, Lee RE. Ureadepsipeptides as ClpP Activators. ACS Infect Dis. 2019 Nov 8;5(11):1915-1925.

Mroue N, Arya A, Brown Gandt A, Russell C, Han A, Gavrish E, LaFleur M. Pharmacodynamics of ClpP-Activating Antibiotic Combinations against Gram-Positive Pathogens. Antimicrob Agents Chemother. 2019 Dec 20;64(1).

Brown Gandt A, Griffith EC, Lister IM, Billings LL, Han A, Tangallapally R, Zhao Y, Singh AP, Lee RE, LaFleur MD. In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci. Antimicrob Agents Chemother. 2018 Aug;62(8).

Conlon, B. P., E. S. Nakayasu, L. E. Fleck, M. D. LaFleur, V. M. Isabella, K. Coleman, S. N. Leonard, R. D. Smith, J. N. Adkins & K. Lewis, (2013) Activated ClpP kills persisters and eradicates a chronic biofilm infection. Nature 503: 365-370.

Gavrish, E., B. Shrestha, C. Chen, I. Lister, E. J. North, L. Yang, R. E. Lee, A. Han, B. Williams, D. Charnuska, K. Coleman, K. Lewis & M. D. LaFleur, (2014) In Vitro and In Vivo Activities of HPi1, a Selective Antimicrobial against Helicobacter pylori. Antimicrobial Agents and Chemotherapy 58: 3255-3260.

Michael LaFleur, Sun L., Keating J., Lister, I., Nantel A., Long L., Ghannoum M., North J., Lee R., Coleman K., Dahl T., Lewis K. (2013) Potentiation of Azole Antifungals by 2-adamantanamine. Antimicrob. Agents Chemother. 57(8):3585-92.

Lewis K. (2013) Platforms for antibiotic discovery. Nat Rev Drug Discov  12:371-387.